Field / Virology

Virology

    New Targeting Vaccines for Sustainable Aquaculture

    Fish diseases represent one of the major risks to the continued growth of the aquaculture industry. This project will develop a flexible and versatile fish vaccine platform (TarGet) where vaccines can be easily tailored to any viral disease and fish species.

    The importance of ISAV HPR0 for causing clinical outbreak of ISA

    The project will develop a method for ranking of individual site risk of ISA (based on the presence of HPR0 and local spread of virulent HPR-deleted ISA virus) by determining a quantitative risk estimate for each site. Such a model will be useful both in terms of more effective and risk-based surveillance, and the possibility to implement more optimal disease prevention. Ranking of sites will be based on factors such as fallowing management, biomass density, mortality, sea temperature, distance to the slaughterhouse, others diseases, lice treatment etc. The analysis will be based on isolated ISA outbreak of 2003-2014, aquaculture data and journal data from the Norwegian Veterinary Institute and knowledge generated in subproject 1.

    Gill disease in Atlantic salmon – studies of multiple factors in challenge models

    Sound gill health is a key-factor for fish growth and welfare. Gill disease contributes with a significant part of disease-related losses in marine farming of Atlantic salmon in Norway. A better understanding of gill diseases, their etiology, pathogenesis and pathophysiology, is needed to develop more effective disease prophylaxis and treatment. The aim of the project is to study the significance and interaction of different factors associated with gill disease, by means of challenge models with live fish.

    HSMI-more. Effects of PRV-infection on Atlantic salmon robustness- more than HSMI?

    Viral infections are among the main challenges linked to loss and reduced growth and performance of farmed salmon in Norway. This project aims to increase the understanding of the interplay between virus, host and environment, to be able to optimize protective procedures.

    ViVaFish - Platform for Fish Virus Vaccines

    Viral diseases represent a huge problem for the global aquaculture industry, and many viral diseases cannot be effectively controlled using the current generation of vaccines. Therefore, new vaccine strategies need to be developed, and basic scientific issues regarding virus agents, host-virus interactions, and the establishment of long term immune protection need to be addressed

    PRV PROTect - Targeting piscine orthoreovirus (PRV) infection in Norwegian Atlantic salmon aquaculture

    Norwegian salmon aquaculture have in the last two decades experienced an increasing number of outbreaks from heart- and skeletal muscle inflammation (HSMI), a disease associated with the piscine orthoreovirus (PRV). This project aim to increase the understanding of how to protect the fish from HSMI, and to what extent the spread of PRV can be limited and controlled by targeted strategies.

    Emerging pathogens in Chilean fish farms

    With the recent discovery of viral agents associated with CMS and HSMI at the Norwegian Veterinary Institute, we believe that both the Norwegian and the Chilean fish farming industry can benefit from a collaboration where these two disease and their associated viruses are studied in more detail. In general, we would like to share our knowledge about emerging infectious diseases in North Atlantic aquaculture with colleagues from Chilean institutions in order to ensure a sustainable and healthy fish farming industry in both countries.

    Vector-borne Infections: risk based and cost effective surveillance systems

    The overall aim of the project is to develop a fully functional framework for a dynamic risk-based surveillance for vector borne diseases. The potential risk of outbreaks of vector borne diseases and consequently the spread within the population at risk will be continuously estimated.

    MOLTRAQ: Molecular tracing of viral pathogens in aquaculture

    The purpose of the project is to increase knowledge on transmission, prevention and control of viral diseases in aquaculture and develop a generic approach to viral disease control by using information on epidemiological and physiogenetical attributes from several important aquatic animal viruses.

    Development of a Piscine Reovirus (PRV) vaccine

    Piscine reovirus (PRV) was recently identified and associated with Heart and skeletal muscle inflammation (HSMI). In this project we aim to develop develop better understanding of PRV virulence and pathology, and a vaccine directed against PRV.

    Characterisation of ISA HPR0 virus- and infection in Atlantic salmon

    In this project we will be investigating molecular-, functional-, pathologicaland evolutionary properties associated with low- or avirulent ISA virus (ISAV) HPR0 genotypes, assumed to be precursors of all virulent ISAV strains that cause classical ISA outbreaks. The main objective through this multidisciplinary approach will be to obtain new information that can aid in forming the necessary basis for evaluating important issues related to HPR0, like the risk of infection and its frequency of transition to virulence.

    Pandemic influenza A (H1N1) 2009 virus in pigs – infection dynamics, genetic variations and pathogenesis

    A new strain of influenza A H1N1 virus, pandemic H1N1 2009 virus (pH1N1-09v), was detected in the spring of 2009. It is unclear whether pigs serve as reservoirs for pH1N1-09v and/or as 'mixing vessels' between pH1N1-09v and other subtypes of influenza to produce new strains with zoonotic potential. In this project we aim to explore the disease dynamics of pH1N1-09v in a pig population that until the outbreak of pH1N1-09v was naïve to influenza.

    Viral Haemorrhagic septicaemia virus (VHSV) in wild and farmed fish in Norway

    Viral Haemorrhagic septicaemia virus (VHSV), the causative agent of viral haemorrhagic septicaemia (VHS), is widespread among several fresh water and marine fish species, both farmed and wild. The presence of VHSV in wild fish has been considered as a threat to the salmonid farming industry.

    VEG-i-TRADE: Impact of climate change and globalisation on safety of fresh produce – governing a supply chain of uncompromised food sovereignty.

    EU-prosjektet VEG-i-TRADE skal fokusere på effekter av forventede klimaendringer og globalisering på mattrygghet, særlig knyttet til vegetabiler. Prosjektet ser på mikrobiologiske og kjemiske trusler for mattryggheten i frukt og grønnsaker.