Biofilm

According to Donlan and Costerton, a biofilm is a microbially derived sessile community characterized by cells that are irreversibly attached to a substratum or interface or to each other, are embedded in a matrix of extracellular polymeric substances that they have produced, and exhibit an altered phenotype with respect to growth rate and gene transcription.

In biofilm, the cells are better protected against external stress, e.g. antibiotics, disinfectants, dessication and nutrient depletion. This can facilitate persistence of pathogens in food and feed production environmets with subsequent crosscontamination of the products, as well as in drinking water pipes. Biofilm may also be formed on food and feedinstuffs itself.

The biofilm resarch at the National Veterinary Institute is focused on zoonictic pathogens like Salmonella, E. coli, mycobacteria, Listeria and moulds.

Contact person National Veterinary Institute:
Live Nesse, Senior scientist, Section of Bacteriology
E-mail: live.nesse@vetinst.no
Tlf.: + 47 23 21 63 15/924 41 267